Dark Souls? Isn't that the game wh-DIRECT INTERVENTION IS NECESSARY.
I'm playing through Mass Effect 2 again with some DLC I couldn't afford the first time around, and I've noticed that I'm taking a lot more renegade interrupts/dialogue choices. Not to my crew, of course, unless they deserve it, but I was a lot ruder to (for example) Warden What's-His-Nuts on Purgatory. I can't really bring myself to heckle Mordin for his work on the genophage, though, in part because I watched his sacrifice on Tuchanka in 3. The first time around, his "it was necessary/for the greater good" rhetoric seemed like blame shifting or even victim blaming (depending on whether you see the krogan as instigators or, y'know, victims).
The other thing I noticed was that the DLC for this game is awesome. Kasumi's adorable and her mission is fun as hell, while Zaeed gives RenShep a run for his/her money in sheer bastard-ness. I also got Overlord (which I haven't played yet) and Wreckage of the Normandy (which made me tear up a little, after firing into the sky twenty-one times).