You stop losing things. In fact, you are absolutely incapable of losing anything. This includes things you actually want to lose, like bad memories or habits. You can't even die, since you stop losing your life as well. You are doomed to walk the earth forever, gradually accumulating the physical and emotional baggage of immortality but unable to do anything about it. You are reduced to a crippled wreck, barely mustering (but not losing) the will to even live, but still firmly connected to reality (since you can't lose your sanity, either). Eventually, you are kidnapped and used by a criminal as a human shield. When that criminal is finally caught by police, you are taken in with him to be experimented on for the rest of eternity.
I wish for awesome music that won't kill anyone upon hearing it, and with no legal repercussions for the ownership thereof.