Sounds like someone who's just got no sense of humor, to me. Seriously, if she can't take a run-of-the-mill schoolroom ribbing, well...tough. I've known alpha bitches like that, think they're the cock of the walk, but the moment someone makes even a tiny, innocuous joke about them, the fucking world's ending or some shit. It doesn't have to be something huge, you could just use an old, grade school "somethin on your nose" joke, and they'd fly off in a pissy little huff.
Now, I'm not saying ya outright mock 'er, or treat 'er like utter shit, but again, if she's a complete cunt, I can't really be arsed to care if she's so pathetic that she can't take an innocent joke.