Should be interesting. Florida is a winner take all state and has 50 delegates up for grabs, more than Iowa, New Hampshire, and North Carolina combined. Whoever wins Florida effectively will officially be the odds-on favorite.
But Florida is a weird ass state. It skews heavily conservative.....except when you are talking about entitlements like Medicare and Social Security, then it skews massively in the other direction. All of the candidates competing in Florida, Romney, Gingrich, and Santorum, have all been vocally critical of Social Security in the past. None of them have gone as far as Perry did by claiming it was nothing but a Ponzi Scheme, but they have all talked about reducing benefits, raising eligibility ages, freezing payments, and severely cutting programs in the interests of balancing the budget. Talking about messing with any benefit or entitlement that impacts seniors will not play well in Florida.
You can't do politics in Florida like you can in tiny New Hampshire, sparsely populated Iowa, or homogeneous North Carolina. Florida is not an even state, it fades from shockingly rural to densely urban, to vast stretches of essential wilderness and wetlands with no one there but natives and the occasional swamp-billy. Florida, unlike the other three early primaries, has several massive media markets, Miami being the largest and most influential, and Miami is one odd demographic. With it's large and very vocal Cuban population, Miami tends to skew damn near jingoistic on foreign policy and socialist on domestic issues. I doubt that Newt has even half the subtlety necessary to navigate the political minefield in Dade county. There's no way Santorum even understands what's on the table in Florida. Romney is the only one with a sufficient political machine and deep enough pockets to manage it, but who knows how the whole Mormon thing will play out among the overwhelmingly Protestant and Jewish retiree population, not to mention the Cubans, who can best be described as "militant Catholic."